Saturday, March 1, 2008

with doubt and in denial

I 'd like to take one more look at this photo taken by Julien, just to get a positive feeling. It constitutes of a rather misleading image of our institute, with lights glooming allover. What it fails to capture, what is impossible to be captured actually, is the obscurity of the greatest part of everyday work produced in this -otherwise idyllic- environment.

Yes, I am being bitter, as you might have expected by the title of this post. Over the last week I have been thinking about a great number of very interesting projects. None of them had an even distant relation to science and the only reason for me calling them "projects" is my almost complete intoxication of "scientificism" of the "geakiest" nature. Thus, what normal people simply define as "interests" or "activities" I have ended up classifying as "projects". And it is exactly this introspection that brought about the aforementioned combination of doubt and denial. But let's take it one at a time.

My increasing doubts in the whole meaning of scientific research were largely speared by a friend's and colleague's (Sylvain's) final talk before leaving the Institute, last Thursday, the most interesting and educating part of which was the following: 5 or 6 consecutive slides quoting the reviewers' comments on a paper of his, finally published in Cell (to the unaware, one of the most highly rated scientific journals in the field of what was formerly known as Biology), after two years of submissions, appeals and re-submissions. Ordinary process one might think. Until you took a look at the reviewers' comments themselves, which were usually mean and rude, most of the times impolite and -most importantly- always contradictory. When one reviewer would talk about a "revolutionary work" the other would have no restrictions in considering the "errors so serious and grave that I [he] would suggest that someone else conducted this analysis". It ended up that it was only due to the strong drive of competitive researchers to publish their work -perseverance was a term which was used more than once throughout this part of the talk- that the paper finally made it through. And, moreover, it was only Sylvain's uncontested optimism that allowed him to carry on, until the final acceptance of the paper.

My optimism, on the other hand, has its limits. And although I 'd like to think that these limits can be stretched quite a lot, they appear to be a bit stiffer when it comes to science. After all, I have been raised and educated to think of research as an objective field, where truth, constantly under the strains of scientific rigour, is safeguarded by personal opinions. How could I then explain so contradictory views on the same piece of work? It looked to me that conducting scientific research could end up being no different than putting out a musical record, publishing a novel or painting a portrait and have half of the critics receive it with glorious reviews, while the rest deny to even compare it with rubbish. I conclude that I refuse to deal with this kind of science. After all, if this is the case, why not try art instead? It's more fun, a lot more rewarding in terms of personal pleasure and by far more useful for society no matter what people may tell you. I mean how many times have you admired a nice scientific paper compared to your favourite song or book, and by the way, DO YOU have a favourite scientific paper or theory? If yes, please stop reading.

To sum up, we are into science for two main reasons. Because it is supposed to be objective and because it pays the rent. Since last Thursday I am convinced that I am only in it for the money. And with this I am also through with denial. Now let me go listen to some Led Zeppelin while taking one more look on my miserably discouraging results.

3 comments:

  1. Well said there.

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  2. No, of course you are not in it for the money (which money?), or for the Nobel prize. You are in it because of a need to explore - like a child that breaks its toys apart just to see how they work.

    Btw, the photo reminded me of "Babel's library" by Borges... And perhaps the situation also - people reading books (i.e. genomes) that have no profound order, seeking for some "justification" in the few meaningless sentences they can trace here and there...

    Keep up - the truth is out there (ok, the last one is a joke).

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  3. First, i am sorry to be the cause of such bad feelings.
    Second, at the reading of this post it sounds a bit like this paper was "mine". Let me please precise that my contribution was relatively small (just in case one of the other authors may have a look here, of course).
    Then, while i acknowledge that my optimism helped me substantially throughout this process, i would like to say that it is not the main reason that made me carry on. The truth is simple and not glorious: i had no choice. I was not the one taking the decisions, and i simply had to do what i was asked to. My resignation was even easier as i could not figure out better alternatives.

    Of course, it is a pain to redo the same things again and again, but this pain is relative. No need to remember our past summer jobs in some corn field or tomatoes greenhouse, we can just consider the endlessly repeated experiments of the biologists we are supposed to help. OK, i know, they are biologists after all, and if we chose bioinformatics it is precisely in order to avoid doing stupid things 10000 times when a computer can do it quickly, and ok, i know, i am certainly not the one who can stand this politically correct speech as i go berserk just thinking about doing more than 3 copy-paste in a row. So yes, it is a (f*) pain (in the *) to redo the same thing again and again. But still, it is a relative pain.

    Of course, it is also frustrating when you know you are right and the referee is wrong.. but i am sure the same frustration is frequent in other jobs (by the way Christoforos, i was referring to science here, not to football). Here, i believe that with a simple hypothesis, appropriate tests, strong evidence and a bit of rationalism and pedagogy any reviewer could be convinced. Or at least we have more objective means to convince the editor that the reviewer is wrong than for instance a politician in front of the parliament.

    As for the real nature of scientific research, i also thought at some point that everything was clear, objective, rigorous. During the thesis i lost my illusions. But not my interest for this job, which -albeit not perfect- is a great job. We can not complain. Why not try art, are you asking? Well, in my case the answer is again simple and not glorious: i have no choice. I am just bad at art, worse than at science. I am not even sure it would be more fun for me, apart from singing maybe (i totally agree that it would be more useful though. Let me quote Julien: "Are we doing something useful? The cleaning lady who comes every evening in our lab is doing something more useful"). In your case, it may be different. Your itinerary is the proof that you have multiple resources. I would even say that you would do a good writer, but i am not qualified to say this. I would also say that it would be a loss for science, and about that i am a bit more qualified. Objectively speaking i mean. Subjectively speaking i would add that it would also be a loss for scientists.

    But i do not have to worry, you do not have your trumpet yet.
    And anyway, you are a geek.

    I am one as well, and even if i do not have a favorite scientific theory (this was great), i like this job as it is, and i hope it would be again the same for you very soon. And still, science is more objective than art. Objectively.
    sy.

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